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Integrating Biomarkers in Clinical Psychology: A Comprehensive Review

Updated: Nov 6, 2023


Abstract

The integration of biomarkers within the domain of clinical psychology has emerged as a transformative approach, bridging the gap between objective biological measures and the intricate realm of psychological experiences and disorders. This comprehensive review delves into the profound significance of biomarkers in mental health assessment and treatment.

The backdrop of rising global mental health conditions and challenges in current diagnostic systems underscores the need for objective measures that provide a comprehensive understanding of mental health conditions. Biomarkers, objectively measurable indicators, offer the potential to transcend the limitations of subjective assessment, paving the way for enhanced diagnostics, prognostics, and personalised interventions. Within the context of the bio-psycho-social model, biomarkers serve as connectors across the facets of mental health, integrating biological, psychological, and social factors.

As the landscape of biomarker research advances, neurobiological domains, imaging techniques, and genetic research converge to yield a comprehensive understanding of the biological underpinnings of mental health disorders. Computational neural networks and artificial intelligence further amplify the potential of biomarkers in diagnostics, therapeutics, and individualised treatment approaches. Through a historical lens, the review explores the evolution of biomarker research, contextualising it within the broader scope of neuroscientific advancements.

Delving into specific biomarkers in mental disorders, the review uncovers insights from electroencephalography (EEG) studies, blood pressure variability (BPV) correlations, and the association between peripheral body temperature rhythm and psychiatric risk. These biomarkers not only provide diagnostic utility but also offer insights into potential prognostic markers and avenues for targeted interventions. However, the integration of biomarkers is not without its challenges. Replicability concerns, biases, and ethical considerations in AI-driven research highlight the need for meticulous methodology and the harmonious amalgamation of objective data and clinical expertise.

As the field of clinical psychology embarks on a paradigm shift towards data-driven, personalised treatments, this review encapsulates the multifaceted landscape of biomarkers. Through the integration of biological, psychological, and technological dimensions, the article emphasises the transformative potential of biomarkers, weaving together diverse disciplines to redefine mental health assessment and treatment approaches.








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